What is a GLP-1?

GLP-1 (glucagon like peptide) is a hormone that is naturally secreted from the gut when eating. GLP-1 medications help your body feel full sooner, stay full longer, reduce constant thoughts about food and regulate blood sugar levels. Semaglutide (brand Wegovy) is FDA approved for chronic weight management. The injectable option is available by prescription and is given once weekly.

What is a GLP-1/GIP?

Like GLP-1, GIP (gastric inhibitory polypeptide) is a gut hormone. Tirzepatide (brand Zepbound) is a GLP-1/GIP dual formulation which regulates blood sugar, helps your body feel full sooner, stay full longer and reduces constant thoughts about food . Tirzepatide is FDA approved for chronic weight management. It is available by injection with a prescription and is given once weekly.

Semaglutide vs Tirzepatide

When combined with a healthy low calorie diet and regular exercise, both semaglutide and tirzepatide have shown to be effective for weight loss. The side effect profile is similar for both. The choice of medication is individualized based on medical history, cost, insurance consideration and previous use of this class of medication.